Xiuling Lu

Professor

Department of Pharmaceutical Sciences


Education

  • Postdoctoral Training: University of Kentucky, Lexington, KY
  • Ph.D. Chinese Academy of Sciences, Biochemical Engineering
  • M.S. Tianjin University of Science & Technology, Fermentation Engineering
  • B.S. Tianjin University of Science & Technology, Biochemical Engineering

Research Focus

  • Nanoparticle-based drug delivery for improving therapeutic indices of anti-cancer agents
  • Image-guided drug delivery for optimizing cancer diagnosis and therapy
  • Neutron-activatable nanoparticles for radiation therapy

Current Publications

  • Glass S, Gonzalez-Fajardo L, O’Reilly Beringhs A and Lu X. Redox Potential and ROS-Mediated Nanomedicines for Improving Cancer Therapy. Antioxidants & Redox Signaling. 2017 Nov 21. doi: 10.1089/ars.2017.7370.
  • Fu Q, Hargrove D, Lu X.  Improving Paclitaxel Pharmacokinetics by Using Tumor-Specific Mesoporous Silica nanoparticles with Intraperitoneal Delivery. Nanomedicine: Nanotechnology, Biology, and Medicine. 2016, 12: 1951–1959.
  • Gonzalez-Fajardo L, Mahajan LH, Ndaya D, Hargrove D, Manautou JM, Liang BT, Chen MH, Kasi RM, and Lu X. Reduced In Vivo Toxicity of Doxorubicin by Encapsulation in Cholesterol-Containing Self-Assembled Nanoparticles. Pharmacological research. 107:93-101.
  • Nguyen CT, Tran TH, Amiji M, Lu X*, Kasi RM*. Redox-Sensitive Nanoparticles from Amphiphilic Cholesterol-Based Block Copolymers for Enhanced Tumor Intracellular Release of Doxorubicin. Nanomedicine: Nanotechnology, Biology, and Medicine. 2015, 11(8): 2071–2082
  • Tran TH, Nguyen CT, Gonzalez-Fajardo L, Hargrove D, Song D, Deshmukh P, Mahajan L, Ndaya D, Lai L, Kasi RM, and Lu X*. Long Circulating Self-Assembled Nanoparticles from Cholesterol-Containing Brush-Like Block Copolymers for Improved Drug Delivery to TumorsBiomacromolecules. 2014, 15 (11): 4363–4375
  • Di Pasqua AJ, Yuan H, Chung Y, Kim JK, Huckle JE, Li C, Sadgrove M, Tran TH, Jay M, Lu X. Neutron-activatable holmium-containing mesoporous silica nanoparticles as a potential radionuclide therapeutic agent for ovarian cancer, Journal of Nuclear Medicine. 2013, 54:111-116.
Xiuling Lu
Contact Information
Emailxiuling.lu@uconn.edu
Phone860-486-0517
Mailing Address69 North Eagleville Road, Unit 3092, Storrs, CT 06269-3092
Office LocationSchool of Pharmacy
CampusStorrs
Linkhttps://lulab.uconn.edu/