Wai Hong (Kevin) Lo

Associate Professor

Connecticut Convergence Institute for Translation in Regenerative Engineering

Department of Medicine

Division of Endocrinology

Department of Biomedical Engineering

Institute of Materials Science


Education

  • Ph.D. in Biochemistry, Hong Kong University of Science and Technology

Research Focus

  • Regenerative engineering utilizing inductive small molecules
  • Targeted drug delivery devices for bone diseases
  • Cytoplasmic dynein molecular motor-based vehicles for intracellular drug and gene delivery
  • Signaling mechanism underlying musculoskeletal regeneration

Current Publications

Carbone, E.J., Rajpura, K., Jiang, T., Kan, H.-M., Yu, X., Lo, K.W.-H., Osteotropic Nanoscale Drug Delivery System via a Single Aspartic Acid as the Bone-targeting Moiety. J. Nanosci Nanotechnol (in press), 2016

Jiang, T., Carbone, E.J., Lo, K.W.-H., Laurencin, C.T. Electrospinning Polymers for Tissue Regeneration. Prog Polym Sci 46, 1-24, 2015

Jiang, T., Yu, X., Carbone, E.J., Nelson, C., Kan, H.-M., Lo, K.W.-H. Poly-aspartic Acid Peptide Linked PLGA-based Nanoscale Particles: Potential for Bone-targeting Drug Delivery Applications. Int J. Pharm 475: 547-557, 2014.

Carbone, E.J., Jiang, T., Nelson, C., Henry, N., Lo, K.W.-H. Small molecule delivery through nanofibrous scaffolds for musculoskeletal regenerative engineering. Nanomedicine: Nanotechnology, Biology and Medicine 10: 1691-1699, 2014

Laurencin, C.T., Ashe, K.M., Henry, N., Kan, H.-M., and Lo, K.W.-H. Delivery of Small Molecules for Bone Regenerative Engineering: Preclinical Studies and Potential Clinical Applications. Drug Discov Today 19:794-800, 2014

Lo, K.W.-H., Jiang, T., Gagnon, K.A., Nelson, C., and Laurencin, C.T. Small Molecule-based Musculoskeletal Regenerative Engineering. Trends in Biotech. 32:74-81, 2014; Cover article featured by the Editor

Cushnie, E. K., Ulery, B.D., Nelson, S.J., Deng, M. Sethuraman, S., Doty, S.B., Lo, K.W.-H., Khan, Y., and Laurencin, C.T. Simple Signaling Molecules for Inductive Bone Regenerative Engineering. PLoS ONE 14;9:e101627, 2014

Ulery, B.D., Kan, H. M., Williams, B.C., Narasimhan, B., Lo K.W.-H., Nair, L.S., Laurencin, C.T. Fabrication of Polyanhydride/Anesthetic Nanoparticles with Tunable Release Kinetics. Adv Healthc Mater  3:843-847, 2014.

Lo K.W.-H., Ulery, B.D., Ashe, K.M., Kan, H.-M. and Laurencin, C.T. Evaluating the Feasibility of Utilizing Small Molecule Phenamil as a Novel Biofactor for Bone Regenerative Engineering. J Tissue Eng Regen Med 8:728-36, 2014.

Lo K.W.-H., Ulery, B.D., Ashe, K. M. and Laurencin, C.T. Studies of Bone Morphogenetic Protein based Surgical Repair.  Adv. Drug Deliv. Rev. 64:1277-91, 2012.

Wai Hong "Kevin" Lo
Contact Information
Emailwlo@uchc.edu
Phone860-679-2949