UConn IMS

Institute of Materials Science Alumni Feature: Ayana Ghosh

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by Paige Bjerke
IMS Written Communications Assistant

Ayana Ghosh ('20)
Ayana Ghosh, Ph.D. (’20)

Ayana Ghosh received her Ph.D. in Materials Science and Engineering from the University of Connecticut in 2020. Afterwards, she joined the prestigious Oak Ridge National Laboratory (ORNL) of the U.S. Department of Energy as a postdoctoral research associate. In 2023, she moved into a full-time position as a staff scientist. In this role, Ghosh has excelled in her research, having won copious awards, spoken at conferences around the world, and gotten published in multiple peer-reviewed journals.

IMS News reached out to Ghosh with five questions about her current position, her many achievements, and her plans for the future.

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You have clearly set yourself apart at Oak Ridge, having won various awards in just a few years. What skills do you feel propelled you to such impressive success, and what support systems, either within your research team or elsewhere, have helped you the most, and how?

Success in research is often non-linear. It involves many days when things don’t work out or…challenges I don’t fully understand. However, I’ve learned that the key to progress is being able to formulate a clear and meaningful scientific problem and then break it down into manageable parts. This helps me maintain a steady pace toward achieving the final goal. I believe that embracing new ideas and constantly learning—despite the challenges—are key drivers of growth and innovation. Above all, consistency, determination, and resilience have been essential to my success. Giving my best effort, even in the face of setbacks, has played a key role in driving my progress.

The support of my mentors during my postdoctoral work (September 2020 to February 2023), ongoing encouragement from my group leader at ORNL, along with the valuable feedback, collaboration, and shared knowledge from my colleagues and collaborators at ORNL and across the globe, have been instrumental in navigating challenges and advancing my work. I continue to stay in touch with my graduate school advisors and faculty, whose guidance remains invaluable in shaping my research journey.

I would like to express my deep gratitude to my mother, whose unwavering support has been a constant source of strength throughout my journey. After the sudden passing of my father during the pandemic in 2021, I faced the challenge of navigating both personal loss and the demands of my academic work. Her courage has been an anchor, helping me to persevere through difficult times and stay focused on my goals.

Working for ORNL, part of the U.S. Department of Energy, how do you grapple with the importance and scale of your work, which undoubtedly shapes government policy and affects the wellbeing of America and the world at large? 

The motivation behind my work has always been the desire to address real-world problems, with the hope to contribute to technological advancements and innovations that improve people’s lives. Working at a U.S. Department of Energy lab, I recognize that my work certainly carries significant weight, particularly knowing that it can influence government policy and ultimately affect the wellbeing of individuals not just in America, but globally. I try to focus on the positive change I hope to drive rather than feel overwhelmed by the scale of it.

I’m also constantly supported by a network of colleagues, mentors, and collaborators who keep me grounded. One of the coolest things about being part of a national lab is the opportunity to casually interact with brilliant minds from various fields. Imagine this: taking an afternoon walk around the building where you might bump into a computer scientist, mathematician, or physicist, and get to chat about the problems you’re working on, gaining fresh perspectives and ideas. It’s amazing how these conversations can spark new ways of thinking, often leading to creative solutions. I also remind myself that progress is often incremental—every small step adds up to a bigger picture. Balancing the scale of my work comes from staying connected to the people and principles that matter most and keeping my focus on the long-term goals.

In 2021, you stated that you “hope to better understand the nuances of experimental research as combined with the particulars of theoretical and simulated data.” Have you been able to gain that understanding at this point in your career? If so, to what extent and how does that understanding inform your current work? If not, what do you feel are the barriers to achieving that understanding?

This is still an ongoing process. Much of my postdoctoral and current work has been dedicated to understanding the nuances between experimental research and theoretical/simulated data. We have made significant strides, particularly in autonomous microscopy, developing machine learning workflows to enhance our understanding of experimental data and integrate it with theoretical simulations.

However, challenges remain, particularly around the disparities between time and length scales. Real-time experiments often don’t align perfectly with theoretical approximations. These gaps require more adaptive approaches. I believe addressing these grand challenges will be crucial not only for my work, but also for improving the synergy between experimental and computational methods. This synergy is essential for unlocking new insights and driving innovation in the world of materials and beyond.

Your Ph.D. thesis was based heavily on machine learning, which you still employ frequently in your work at ORNL. What should current students in the field of materials science know about machine learning and AI, and how would that knowledge benefit them? 

For graduate students in materials science, getting comfortable with the basics of ML and AI is crucial. Start by understanding the algorithms, their implementation, and how to apply them to real-world problems. The key is knowing when and how to use these tools, based on solid domain expertise. It’s not just about using fancy algorithms or architectures, it’s about identifying the problems in materials science that can benefit from them. Beyond just applications, there’s also a big opportunity for students to get involved in method development to push the boundaries of what’s possible.

On a broader note, AI is shaking up every field – it’s changing how we teach and learn, too. With AI-assisted teaching, personalized learning, and a wealth of accessible tools, I think we’re on the brink of a classroom revolution. It’s an exciting time. I imagine embracing these changes will only make us all better researchers and learners. So, for students, one piece of advice, don’t just sit back – dive in and start experimenting (in the lab and on the computer)!

With so much recognition already, and new projects going on constantly, what are your goals or specific things you want to achieve over the next 10 years?

Looking ahead, I am committed to pushing the boundaries of my field by advancing technological solutions that tackle some of the world’s most pressing challenges in energy, AI, and quantum technologies. I am particularly excited about the potential of deepening our understanding of the foundational principles of materials physics and bridging theory with real-world experiments. This integration will be crucial in developing practical, scalable solutions that address the evolving challenges in both society and technology.

With an eye on what’s next, my goal is to take on more leadership roles, collaborating with a diverse range of experts across disciplines to drive innovation and create meaningful change. Equally important is my commitment to mentoring young researchers and contributing to the development of the next generation of scientists. At the same time, I recognize the importance of balancing career advancement with maintaining personal well-being, ensuring both professional growth and personal fulfillment.

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IMS News thanks Dr. Ghosh for taking the time to answer our questions and providing such potent insight into her work. We wish her all the best as she continues her exciting and innovative career journey.

 

Avinash Dongare Named ASME Fellow

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Avinash Dongare
Dr. Avinash Dongare

by Linda Costa
IMS Written Communications Assistant

Dr. Avinash Dongare, a resident member of the University of Connecticut’s Institute of Materials Science (IMS) has been elected Fellow of the American Society of Mechanical Engineers (ASME).  Dr. Raj Rajendran, Chair of the Executive Materials Division of ASME, surprised Dongare with the nomination.

Dr. Rajendran has known Avinash since 2007 when they met while Dr. Rajendran was serving as Chief Scientist for the Engineering Directorate at the U.S. Army Research Office.  During that time, Dongare was serving as Rajendran’s National Research Council (NRC) Fellow, working on modeling the response of complex molecules and single crystals under shock (high pressure and high strain rate) loading conditions.

“It is clear that Dr. Dongare stands among the most outstanding researchers of his generation,” Dr. Rajendran said of his decision to nominate Dongare. “I am confident his innovative research will continue to earn him well-deserved recognition and accolades from his peers.”

Rajendran also noted Dongare’s dedication to the field, noting that he actively serves the scientific community through his roles with ASME and as a reviewer for several leading journals in his area of expertise.

“His service and leadership underscore his commitment to advancing science and supporting the work of his colleagues,” Dr. Rajendran commented.

Dr. Dongare’s current research involves the development and application of advanced computational methods to investigate the behavior and properties of novel materials across multiple scales.

ASME is a nonprofit organization founded in 1880 to help the engineering community develop solutions to numerous challenges.

Qiaoling Fan from Hohman Group Published in JACS

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Qiaoling Fan
Ph.D. student, Qiaoling Fan, is a member of Professor J. Nathan Hohman’s group

by Linda Costa
IMS Written Communications Assistant

Qiaoling Fan, a member of IMS resident faculty member and Professor of Chemistry, Nathan Hohman’s research group, has been published in JACS (the Journal of the American Chemical Society). Fan is currently a third-year graduate student in inorganic chemistry here at the University of Connecticut.

JACS is a weekly scientific journal published by the American Chemical Society. Published research undergoes a rigorous peer-review process.

Fan’s research, entitled Nucleophilic Displacement Reactions of Silver-Based Metal-Organic Chalcogenolates (MOChas), provides a new synthetic route for the preparation of more elaborate MOChas and heterostructures. Her research has also enabled the preparation of unreachable oligophenyl MOChas which lead to an applicable platform to create complex 2D inorganic phases.

The Hohman Research Group currently includes eight graduate students and one undergraduate student. The group’s research focuses on the design and synthesis of nanomaterials and nanointerfaces for applications, understanding origins of how different structure leads to function in complex materials, and solving synthetic problems. Their work has earned a Department of Energy (DoE) grant to help further their research.

“Working with Dr. Hohman’s group has been fulfilling, both intellectually and creatively,” Fan says. “Collaborating with talented peers in Dr. Hohman’s lab has been a constant learning experience, fostering interdisciplinary thinking and dynamic idea exchanges. What excites me most about our research is its potential real-world impact, particularly in display technology.

Fan earned her Bachelor of Science degree from Sichuan Normal University in Chengdu, China followed by a master’s in chemistry at East China Normal University in Shanghai, China. She also spent time as a high school chemistry teacher in China.

“Teaching at this level was a unique experience that helped me grow both professionally and personally,” fan recalled. “One of the most rewarding aspects of teaching was watching my students grow and develop a curiosity for chemistry. What I hoped my students would take away from my teaching was not just a set of chemical facts but an appreciation for the scientific process and the world around them.”

Collaborative Research Paves Way for High-Performance Fiber Materials

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Dr. Yao Lin

by Linda Costa
IMS Written Communications Assistant

A research study recently published in the Journal of the American Chemical Society (JACS) presents a breakthrough in the design of synthetic copolypeptides which mimic the mechanical properties of spider silk.

The study, entitled Synthesis and In Situ Thermal Induction of β-Sheet Nanocrystals in Spider Silk-Inspired Copolypeptides, was conducted in the research lab of IMS resident faculty member and Professor of Chemistry, Dr. Yao Lin, in collaboration with Dr. Jianjun Cheng, Professor of Materials Science and Engineering at the University of Illinois Urbana Champaign (UIUC). Graduate students Tianjian Yang and Jianan Mao (UConn) and Tianrui Xue (UIUC) provided essential contributions to the study.

Leveraging advanced helix-accelerated, ring-opening polymerization techniques, the research team synthesized multiblock copolypeptides, which undergo a transformation into β-sheet nanocrystals upon heating, achieving robust materials with excellent mechanical integrity, tunability, and processability without the need for solvents.

The study also expands upon traditional poly-alanine-based constructs found in natural spider silk by introducing novel β-sheet-forming amino acids, offering new ways to tailor these materials for specific functional applications. This approach is expected to pave the way for next-generation biopolymer and high-performance fiber materials whose properties will include increases in tensile strength, extensibility, processability, and versatility similar to natural spider silk.

Professor Lin’s group studies bio-inspired macromolecules and materials using the techniques of polymer synthesis, macromolecular characterization, physical chemistry, molecular biology and biochemistry as tools.

Visit the JACS site to read the research.

Ki Chon Named Board of Directors Distinguished Professor

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Ki Chon
Dr. Ki Chon

Dr. Ki H. Chon, the Krenicki Professor of Biomedical Engineering at the University of Connecticut, is a pioneer in the field of biosignal processing and wearable devices. As the inaugural head of the Biomedical Engineering department from 2014 to 2022, Dr. Chon’s leadership was instrumental in driving substantial growth in both faculty recruitment and research funding, securing a more than $17 million increase in annual research allocations.

Having earned his undergraduate engineering degree from UConn, Dr. Chon has remained dedicated to advancing his alma mater’s stature in the global academic community. His research has led to the development of a life-saving wearable device capable of predicting seizures in divers—a breakthrough that underscores his commitment to translating academic research into practical, real-world applications. This innovation has not only secured the backing of the U.S. Navy but also holds the potential to transform safety protocols in diving operations worldwide.

Dr. Chon’s scholarly contributions are extensive, with an impressive tally of over 220 refereed journal articles and 13 U.S. patents granted, alongside substantial federal research funding totaling more than $29 million. His work on real-time detection of atrial fibrillation and other physiological anomalies via mobile and wearable technology platforms has positioned him at the forefront of biomedical engineering.

Dr. Chon has demonstrated a profound commitment to educational innovation. He has developed three new courses, including Junior Design and Biomedical Signal Processing, which have significantly enhanced the biomedical engineering curriculum at UConn. These courses not only prepare students for real-world engineering challenges but also ensure that they are well-versed in the latest technological advancements and methodologies.

Beyond his technical and academic achievements, Dr. Chon has played a pivotal role in enhancing the department’s diversity and inclusion efforts. His recruitment strategy led to the appointment of UConn’s first female African American Professor in the College of Engineering, marking a significant step forward in fostering an inclusive academic environment.

As a fellow of six major societies and a distinguished member of the Connecticut Academy of Science and Engineering, Dr. Chon’s contributions to the field of biomedical engineering are widely recognized. His leadership and vision have not only elevated the Department of Biomedical Engineering at UConn but have also had a profound impact on the broader scientific and engineering communities.

In recognition of his outstanding contributions to research, teaching, and service, Dr. Ki H. Chon is an exemplary candidate for the Board of Trustees Distinguished Professor award. His ongoing dedication to the field and his alma mater makes him a deserving recipient of this prestigious honor.

Three Students from Duduta Group Awarded NASA CTSGC Fellowships

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Duduta group members surround logo of NASA CT
Dominic Flores (top), Sahib Sandhu (bottom left) and Alexander White (bottom right) from the Duduta Group

NASA Connecticut Space Grant Consortium (CTSGC) is a federally mandated grant, internship, and scholarship program funded as a part of NASA Education. Formed in 1991 by Trinity College, University of Connecticut, University of New Haven, and University of Hartford, NASA CTSGC encourages broader participation in NASA research programs.
Three graduate students from Prof. Mihai “Mishu” Duduta’s group (Dominic Flores, Sahib Sandhu and Alexander White) have won NASA Connecticut Space Consortium Graduate Fellowships of $10,000 each to support research at the interface of soft and space robotics.

Dominic Flores was awarded $10,000 for his research proposal entitled Dielectric Elastomer Actuator Grippers with Sensing Capabilities for Space Applications.

Sahib Sandhu was awarded $10,000 for his research proposal entitled Space ready deployable composites based on compliant capacitors.

Alexander White was awarded $10,000 for his research proposal entitled Spacecraft Landing System using Soft Tunable Tensegrity Structures.

IMS congratulates Dominic, Sahib, and Alexander!

Alex Asandei Awarded 6th Consecutive Single-PI NSF Grant

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Alexandru Asandei
Dr. Alexandru Asandei

With the support of the Macromolecular, Supramolecular and Nanochemistry program in the National Science Foundation (NSF) Division of Chemistry, Associate Professor of Chemistry and faculty member in the IMS Polymer Program Alexandru D. Asandei,  is developing new methods for the precise synthesis of novel fluorinated polymeric materials with complex architectures, as well as exploring the re/upcycling of commercial fluoropolymers.

Fluoropolymers are contrasted to conventional polymers with even simple homo/random fluoropolymers exhibiting outstanding chemical, thermal and flame resistance, biocompatibility, and unique electronic properties which render them important in high-end applications such as battery, aerospace, sensing, medical device, building, construction, and automotive industries. However, the chemical tools for the precise synthesis of analogous complex fluoropolymer materials (blocks, grafts etc.) are lacking. Thus, the project goals include the development of the required novel chemistry, to explore hitherto unknown and unavailable materials with potentially superior properties and applications leading to the associated societal benefits.

While technologically important, fluoropolymers suffer from a number of factors that have hampered new developments. These factors include a combination of very low monomer reactivity, very high propagating polymer chain end reactivity, complex and often hazardous laboratory setups, and the general lack of appropriate polymer chemistry tools (initiators, catalysts, coupling agents etc.). Accordingly, fluoroalkenes remain some of the most challenging monomers for both controlled radical and coordination polymerizations, where manipulation of molecular weight, polydispersity and architecture/sequence are of paramount importance for the emerging properties. In addition, current re/upcycling of industrial fluoropolymers remain minimal.

The proposed research aims at developing innovative and environmentally conscious chemistry (e.g. water, visible light catalysis etc.), to overcome the above deficiencies, and significantly enlarges the fluoro, organic and polymer synthesis toolbox, while providing access to novel fluoropolymer materials. This includes the elaboration of novel, functional, universal radical initiating systems that enable both controlled radical fluoro/regular alkene polymerizations and chain end derivatizations/couplings towards the synthesis of multiblock copolymers, in-depth mechanistic investigations on optimizing polymerization parameters and understanding the structure/property/function in the resulting fluoropolymers, as well as exploration of the coordination polymerization of fluoroalkenes, and the up/recycling of industrial fluoropolymers.

The project provides training and education to undergraduate and graduate students, including minority and female students, in synthetic organic, organometallic, and polymer chemistry. The project also has strong industrial impact, important outreach activities, and the results will be broadly disseminated in the scientific literature and national and international meetings.

UConn Signs Contract With Air Force Research Laboratory

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from the Department of Materials Science and Engineering

A robotic welding arms in operation.
A robotic welding arms in operation.

UConn recently received $10.5 million from the Air Force Research Laboratory (AFRL) for research on high-temperature materials and manufacturing processes. The funding will allow a team of seven faculty members from Materials Science and Engineering (Professors Aindow, Alpay, Frame, and Hebert), Civil and Environmental Engineering (Professor Kim), Mechanical Engineering (Professor Bilal), and Chemistry (Professor Suib) along with post-doctoral associates and graduate assistants to address challenges in the manufacturing of aerial systems intended to fly at high speed. Much of the four-year research project will focus on welding-related challenges for high-temperature metallic materials that are used for structures exposed to high speeds. The UConn team will combine experimental and theoretical approaches to help their collaborator, RTX, advance their manufacturing solutions. Additional project tasks address the behavior of non-metallic high-temperature materials under different processing and service conditions, additive manufacturing of high-temperature refractory metals, and the design and processing of metamaterials. These metamaterials are designed to change heat- and electro-magnetic fields in and around structures and are considered to advance the thermal management of high-temperature structures.

The new AFRL project comes at the heels of previous and ongoing AFRL projects for UConn approaching $30 million that involve over 15 faculty members from the Colleges of Engineering and Liberal Arts and Sciences with dozens of graduate students and post-doctoral associates. Covering research from functional materials and photonics to casting, welding, and additive manufacturing, the UConn team has established itself as a valuable partner for the AFRL and key industry partners, for example, Pratt & Whitney and Collins Aerospace.

Professor Rainer Hebert says of the contract, “The AFRL funding enables the UConn team to pursue materials processing research with a strong focus on industry and government relevance. Students and post-doctoral associates working on the project see firsthand how their research translates to industry. This insight will help in preparing a workforce that can pursue research excellence with a keen sense of the needs and constraints of industrial applications.”

12 UConn Faculty Elected to CASE

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CASE 2024 new members from IMS
(l to r) Drs. Bodhisattwa Chaudhuri, Yupeng Chen, Avinash Dongare, Liisa T. Kuhn, and David Pierce are among the 12 UConn faculty selected as members of CASE for 2024.

The Connecticut Academy of Science and Engineering (CASE), an organization of academic and industry professionals who advise the state government on matters of science and industry, announced the election of 35 new members in 2024. Twelve of these new members — over a third — are UConn faculty. Nearly half of those selected from UConn are members of the Institute of Materials Science (IMS).

  • Bodhisattwa Chaudhuri, Professor, UConn School of Pharmacy
  • Yupeng Chen, Associate Professor, Biomedical Engineering, UConn College of Engineering
  • Avinash Dongare, Professor, Materials Science and Engineering, UConn College of Engineering 
  • Liisa T. Kuhn, Professor and Associate Department Head, Biomedical Engineering, UConn Health 
  • David Pierce, Professor, Mechanical, Aerospace and Manufacturing Engineering, UConn College of Engineering

All new members will be introduced at the Academy’s 49th Annual Meeting and Dinner at the Woodwinds in Branford, CT on May 21, 2024. IMS congratulates all the new CASE members.

Read the full story at UConn Today

Jessica Rouge Empowers Underrepresented Women in Science

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Jessica Rouge (far left) with the members of her lab (UConn Photo).

Before sunrise, Jessica Rouge used to leap out of bed in the glow of darkness and race to the Charles River with her teammates for crew practice.  

A few hours later, the future UConn associate chemistry professor would run back to Boston College for her morning science class: she was among a small group of female students pursuing a B.S. degree in biochemistry. 

Rouge still sprints, but in a different way: now, she doubles as teacher, mother to two toddlers, mentor to young scientists, hobby musician and soon she will potentially add another role to her repertoire: science entrepreneur. 

Rouge’s lab group, which is more than 50 percent female, “seeks to understand how enzymes and nucleic acids can be used in new ways to engineer highly specific and targeted responses in chemical and biological systems. Specifically, her team is interested in developing new chemical strategies for assembling catalytic RNA sequences at nanoparticle surfaces for sensing, diagnostic, and therapeutic applications.” 

Rouge was a 2022-2023 recipient of the SPARK Technology Commercialization Fund, a program that helps shepherd the process of translating invention to entrepreneurial success. 

With the preclinical data she was able to secure using the Spark Fund resources, Rouge is hopeful that she and her collaborators are close to licensing her technology. 

Read the full story at UConn Today